Allergen Immunotherapy safe and effective therapy for allergic Rhinitis with Rheumatic Autoimmune Disease
Allergen Immunotherapy was found to be a safe and effective treatment modality in patients with allergic rhinitis complicated by Rheumatic Autoimmune Disease according to a study published in the journal, Allergy, Asthma & Clinical Immunology, 2022.
Allergic Rhinitis (AR) is a common allergic disease that is caused by an IgE-mediated inflammation of the upper respiratory tract. Allergen Immunotherapy (AIT) has modified the natural history of allergic diseases. AIT has been absolutely or relatively contraindicated in patients with Rheumatic Autoimmune diseases (RADs) as the overall effect of AIT on the immune system has not been explored much. As there were no long-term studies on patients with RADs receiving AIT, researchers from Japan conducted a study to evaluate the safety and effectiveness of AITs in patients with RADs.
A single-center retrospective observational study was conducted on RAD patients receiving AIT for AR. Changes in the activity of RAD patients who were undergoing AIT treatment were investigated for 2 years from baseline, including those who discontinued it. Using the Japan Allergic Rhinitis Standard Quality of Life Questionnaire the effectiveness of AIT was investigated.
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