Amoxicillin best for treatment of acute otitis media in children: study
Amoxicillin showed better efficacy than other antibiotic agents for the treatment of acute otitis media in children according to a recent study published in the Journal of Pediatrics.
Acute otitis media (AOM) is defined as an infection of the middle ear and is the second most common pediatric diagnosis in the emergency department following upper respiratory infections. Although acute otitis media can occur at any age, it is most commonly seen between the ages of 6 to 24 months
A study was conducted to compare the antibiotic treatment failure and recurrence rates between antibiotic agents (amoxicillin, amoxicillin-clavulanate, cefdinir, and azithromycin) for children with uncomplicated acute otitis media (AOM)
They completed a retrospective cohort study of children 6 months-12 years of age with uncomplicated acute otitis media identified in a nationwide claims database. The primary exposure was antibiotic agent, and the primary outcomes were treatment failure and recurrence. Logistic regression was used to estimate odds ratios and analyses were stratified by primary exposure, patient age and antibiotic duration.
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