Head and neck cancers: Prolonged-Chemoprophylaxis reduces VTE risk
Venous thromboembolism (VTE) is associated with substantial morbidity and is the most common factor associated with preventable death among hospitalized patients. Recent study findings indicate that prolonged-duration chemoprophylaxis among patients with head and neck cancer undergoing oncologic procedures may be associated with reductions in perioperative venous thromboembolism. The research has been published in theJAMA Otolaryngology-Head & Neck Surgery on January 14, 2021.
Professor Armand Trousseau was the first to write about the association between cancer and thrombosis in 1865, and the combination of the two conditions is still often called Trousseau's syndrome. Venous thromboembolism (VTE) is reported to occur in up to 33% of patients undergoing major vascular surgery. Despite this high incidence, patients inconsistently receive timely VTE chemoprophylaxis. The risk of VTE among patients receiving delayed VTE chemoprophylaxis is unknown. Therefore, researchers of the State University of New York Upstate Medical University, Syracuse, conducted a study to assess the association between prolonged duration chemoprophylaxis (PDC) and VTE in high-risk patients with head and neck cancer undergoing oncologic procedures.
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