Magnetic Resonance Imaging Can Detect Meniere Disease, discovers study

In this prospective study, researchers included a total of 117patients with definite MD. The diagnostic criteria were based on the latest guidelines revised in 2015. All the patients received IT-Gd 24 hours prior to MRI by injection through the tympanic membrane. All patients were followed at 1 week, 1, 3 and 6 months after the examination. The primary outcome assessed was diagnostic sensitivity and specificity of MRI findings.

Key findings of the study were:

• Upon analysis, the researchers noted that the diagnostic sensitivity and specificity of MRI were 79.2% and 80.7% respectively.
• However, they found no significant correlation between hearing levels and cochlear grading scores, nor vestibular grading scores.
• They also found no significant association between duration of disease and cochlear or vestibular grading scores.
• They noted 26 patients had false-negative MRI results and 21had false-positive MRI results.
• Further, they reported no significant adverse reactions to IT-Gd injection, and all patients healed within one week.

The authors concluded, "Considering the high sensitivity and specificity, IT-Gd MRI offers reliable imaging diagnostic criteria for MD."

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DOI: https://doi.org/10.1038/s41598-021-86589-1