Multimodality therapy including surgery improves survival in sinonasal squamous cell carcinoma: Study
Recent research has found out that multimodality therapy, including surgical intervention, associates with improved overall survival (OS) after multifactorial adjustments and that induction chemotherapy (IC) followed by surgery associated with improved OS compared to induction chemotherapy (IC), followed by chemoradiation therapy (CRT) and CRT alone.
The study is published in the International Forum of Allergy and Rhinology.
Sinonasal squamous cell carcinoma (SNSCC) is a rare malignancy that poses management challenges. Although surgery and chemoradiation therapy (CRT) remain therapeutic mainstays, induction chemotherapy (IC) has emerged as a useful adjunct with locally advanced disease.
Hence, Nyssa Fox Farrell and colleagues from the Department of Otolaryngology–Head and Neck Surgery, Division of Rhinology and Sinus Surgery, Oregon Health and Science University, Portland, OR used the National Cancer Data Base (NCDB) to examine treatment outcomes for patients diagnosed with SNSCC.
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