India issues alert to deter use of Roche's Avastin drug for eyes

However, fifteen patients at a hospital in western Gujarat state underwent surgery last week when they reported swelling and pain in their eyes following usage of Avastin.

The advisory, issued by India's top drugs regulator G.N. Singh, comes two days after Reuters reported Gujarat had asked distributors to recall one batch of the medicine, while the southern state of Telangana ordered a freeze on all its batches.

"Regulatory authorities may alert their inspectorate staff to monitor the movement of the said drug and its use in ophthalmology," Singh wrote in the alert notice, adding the drug was not approved in India for such usage.

Roche's India unit said it was aware of the government notification and reiterated it does not promote use of Avastin for eye ailments for which it does not have an approval.

Still, the company said on Tuesday it was taking events in Gujarat "very seriously" and initiated an internal probe.

The C.H. Nagri Municipal Eye Hospital in Gujarat's Ahmedabad city administered the drug to 7,000 people over the last decade but has now stopped.

Cases of shoddy medical treatment and spurious drugs are often reported in India, where the public health system remains overburdened and people, especially in smaller towns and villages, struggle to access basic health services.

Gujarat authorities are also investigating whether the drug involved in last week's incident was a fake copy of Avastin.