Nocturnal Acid Breakthrough and the role of Vonoprazan - Dr Roy Patankar
Nocturnal acid breakthrough (NAB) is defined as a prolonged drop in intra-gastric pH below 4 for over 60 minutes during nighttime hours, a phenomenon that impacts 40% to 70% of GERD patients even when they are on proton pump inhibitors (PPIs). NAB can lead to discomfort and disrupt sleep, as PPIs sometimes fail to maintain adequate acid suppression throughout the night.
In this video, Dr Roy Patankar, a Gastrointestinal Surgeon, Laparoscopic Surgeon, and Digestive Endoscopist from Mumbai, offers his expertise on understanding and managing NAB. Dr Patankar delves into effective management approaches, including the role of Vonoprazan, a potassium-competitive acid blocker. He also discusses the practical advantages of Vonoprazan over traditional PPIs in achieving consistent overnight acid suppression, which may bring relief to GERD patients experiencing NAB.
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