NSAIDs can lead to exercise induced anaphylaxis
Severe allergic reactions, known as anaphylaxis, are scary, and it can sometimes be hard to determine the cause. A new medically challenging case presented at this year's American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting reports a situation in which a non-steroidal anti-inflammatory drug (NSAID) caused an anaphylactic reaction in a female runner. NSAIDs are medicines that are widely used to relieve pain, reduce inflammation, and bring down a high temperature.
"We saw a 40-year-old avid runner in our clinic who had no history of food or medication allergies," says Sebastian Sylvestre, MD, ACAAI member and lead author of the abstract. "She had previously tolerated NSAIDs, and she took naproxen before her marathon training run. By mile four she had developed itching and swelling around her eyes. By mile six she had hives, lightheadedness, difficulty breathing, and vomiting. Her husband brought her to the emergency room for treatment."
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