Research Identifies Altered Serum Protein Linked to Periodontitis and Cardiovascular Disease
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Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umea University, Sweden. These findings published in the Journal of Dental Research pave the way for research into biomarkers for periodontitis and the underlying causes of the disease.
Researchers at Umeå University have now shown that individuals with periodontitis exhibit a unique inflammatory protein profile in their blood. The findings indicate, among other things, that severe periodontitis is associated with significantly reduced levels of a protein called EGF -epidermal growth factor, which is crucial for wound healing. The levels of a protein associated with cardiovascular disease, OLR-1 -oxidized low-density lipoprotein 1, are also significantly lower in individuals with severe periodontitis compared to healthy individuals.
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