Chondroitin sulfate reliable treatment option for diabetic osteoporosis patients

Published On 2021-12-12 02:09 GMT   |   Update On 2021-12-15 05:47 GMT
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A new study by Shan Shan Qi and the team revealed chondroitin sulfate could prevent streptozotocin (STZ)-induced diabetic osteoporosis (DOP) and repair bone microstructure. The main mechanism is through regulating bone metabolism, anti-oxidation, and anti-inflammatory. The findings of the study, published in the Frontiers in Endocrinology, indicate that chondroitin sulfate could be used for the development of anti-DOP functional foods and diet interventions for diabetes.

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The results showed that chondroitin sulfate can reduce blood sugar and relieve symptoms in diabetic rats. In addition, it can significantly increase bone mineral density, reduce bone marrow adipocyte number in diabetic rats, and improve bone microstructure. After 10 weeks of chondroitin sulfate administration, the SOD activity level was upregulated, as well as CAT levels, indicating that chondroitin sulfate can alleviate oxidative stress in diabetic rats.

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Chondroitin Sulfate Reliable Treatment For Diabetic Osteoporosis: Study


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