Heart Failure, diabetes patients benefit from metformin
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A recent study involving older U.S. adults hospitalized for heart failure (HF) with comorbid diabetes found metformin initiation to be independently associated with substantial improvements in 12-month clinical outcomes. This was driven by findings among patients with an ejection fraction (EF) >40%. Conversely, regardless of EF, sulfonylurea initiation was related to excess risk of death and HF hospitalization.
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