Heart Failure, diabetes patients benefit from metformin
A recent study involving older U.S. adults hospitalized for heart failure (HF) with comorbid diabetes found metformin initiation to be independently associated with substantial improvements in 12-month clinical outcomes. This was driven by findings among patients with an ejection fraction (EF) >40%. Conversely, regardless of EF, sulfonylurea initiation was related to excess risk of death...
A recent study involving older U.S. adults hospitalized for heart failure (HF) with comorbid diabetes found metformin initiation to be independently associated with substantial improvements in 12-month clinical outcomes. This was driven by findings among patients with an ejection fraction (EF) >40%. Conversely, regardless of EF, sulfonylurea initiation was related to excess risk of death and HF hospitalization.
According to the study, starting metformin treatment in patients with type 2 diabetes shortly after they were hospitalized for heart failure was linked with a reduced rate of repeat hospitalization for heart failure (HHF) during the subsequent year when their left ventricular ejection fraction (LVEF) was greater than 40%.
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Metformin improves outcomes in patients with HF and diabetes, finds Study
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