'DNA Diet' may help lower health risks related to high blood sugar : Study
A study conducted by Imperial College London and DnaNudge found that personalized dietary advice based on genetic information, along with in-person coaching from a healthcare professional, was more effective at lowering blood glucose levels than standard dietary coaching.
The results are Published in the Journal Nature Scientific Reports.
Pre-diabetes occurs when blood glucose levels are consistently elevated but not yet at the level of type 2 diabetes (T2D). While pre-diabetes is reversible, if left untreated, up to 10% of individuals with pre-diabetes progress to T2D annually. T2D is a leading cause of sight loss, kidney failure, heart attacks, stroke, and lower limb amputation, affecting 90% of the 4.9 million people living with diabetes. However, lifestyle changes have been shown to significantly reduce this risk. Moreover, genetic traits can provide insights into an individual's susceptibility to diet-related chronic conditions, highlighting the importance of personalized dietary modifications to mitigate these risks.
To understand the impact of DNA-based diets on pre-diabetes, researchers enlisted 148 individuals with elevated blood sugar levels. Baseline measurements of fasting plasma glucose (FPG) and glycated haemoglobin (HbA1c) were taken, along with dietary information. Participants were then divided into three groups: a control group receiving NICE-guided coaching, an intervention group receiving coaching and a DNA-based diet, and an exploratory group using DnaNudge's app and wearable device for self-guided DNA-personalized food recommendations. FPG and HbA1c levels were reassessed at 6, 12, and 26 weeks.
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