Hepatitis B Vaccine May Lower Diabetes Risk: Study Finds
A new study to be presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) and published in the journal Diagnostics has found that individuals with hepatitis B virus (HBV) immunity, achieved through vaccination, may have a lower risk of developing diabetes.
The liver plays a central role in glucose metabolism, and HBV infection is believed to impair liver function, disrupting metabolic pathways and increasing the likelihood of abnormal blood sugar levels and diabetes. While HBV vaccination protects against infection, its role in diabetes prevention among uninfected individuals has remained unclear until now.
To explore this, the researchers conducted a retrospective cohort study using anonymized electronic medical records from the TriNetX global health research platform. Data were collected from 131 healthcare organizations across the US, Europe, Middle East, Africa, Asia Pacific, and Latin America. The study included adults aged 18 and above who had hepatitis B surface antibody (HBsAb) test results and no history of HBV infection. Participants were classified as HBV-immunised (HBsAb ≥10 mIU/mL) or unimmunised (HBsAb <10 mIU/mL).
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