How Mitochondrial Defects Impair Insulin Production in Type 2 Diabetes? Study Sheds Light
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In a study published in Science, researchers at the University of Michigan used mice to show that dysfunctional mitochondria trigger a response that affects the maturation and function of insulin-producing pancreatic β-cells.
Mitochondrial defects are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin produced by their pancreas to keep their blood sugar at normal levels.
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