Is Diabetes drug Mounjaro also effective for weight loss? Nature Medicine Study sheds light!

The results were nothing short of remarkable. The group treated with tirzepatide showed an additional average weight loss of 18.4% compared to the 2.5% weight gain in the placebo group, highlighting an estimated treatment difference of -20.8 percentage points. The percentage of individuals achieving an additional weight reduction of 5% or more was also significantly higher in the tirzepatide group at 87.5% compared to only 16.5% in the placebo group.

Furthermore, the study noted that tirzepatide's side effects were primarily gastrointestinal and mostly mild to moderate in severity, showing that the treatment was generally well-tolerated.

Reference: Wadden, T.A., Chao, A.M., Machineni, S. et al. Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial. Nat Med (2023). https://doi.org/10.1038/s41591-023-02597-w