The increased fracture risk in patients using insulin compared to metformin
Patients with type 2 diabetes have an increased risk for fractures, despite their normal-to-high bone mineral density, according to research being presented Saturday, June 11 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.
"Patients using insulin or sulfonylurea are at a high risk of fractures compared to metformin-only users, and the risk could be higher in non-obese and well-controlled diabetic patients," said Sung Hye Kong, M.D., of Seoul National University Bundang Hospital in Seongnam, South Korea.
Kong and colleagues acknowledge that anti-diabetic medications have long been suspected for an increased risk for fractures among this patient population. However, after investigating longitudinal comparative studies, they learned that evidence of these effects are limited.
For their study, the researchers included 6,694 patients aged ≥50 years from the common data model (CDM) database between 2008 and 2011, who used the same anti-diabetic medications for over a year.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.