Vitamin D deficiency Prevalent in T2DM patients
Vitamin D plays an important role in bone and modulates mineral metabolism and immune function with a probable link to several chronic and infectious conditions. In vivo studies have revealed that vitamin D deficiency reduces insulin secretion capacity and several studies have also shown a correlation between vitamin D levels and insulin resistance, nonetheless, extensive studies showing the relationship between the two are lacking especially among the southern Indian population.
The present study published in the Journal of the Association of Physicians of India was aimed at evaluating the relationship between vitamin D and insulin resistance by using the homeostatic model assessment-insulin resistance (HOMA-IR).
The cross-sectional study included 184 people among which 92 were diabetic and 92 were nondiabetic. Fasting serum insulin (I0), fasting plasma glucose (G0), hemoglobin A1c (HbA1C), renal function test, liver function test (LFT), lipid profile, and vitamin D levels were all estimated.
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