Can exercise protect against fatty liver associated diseases

 Worldwide one in four persons  is reported to suffer from non-alcoholic liver disease (NAFLD, also called metabolic liver disease MAFLD). Those affected often have type 2 diabetes as well as an increased risk of liver cirrhosis and cardiovascular diseases. Exercise not only trains the muscles but can also prevent the development of fatty liver.

A new study by the German Center for Diabetes Research (DZD), Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in particular of the liver mitochondria, can be observed in this process. The study has now been published in Molecular Metabolism.

 In addition, NAFLD is associated with increased mortality. An imbalance between energy intake and consumption is discussed as a cause for the disease. This leads to fat deposits in the liver and over time impairs the function of the mitochondria  – both risk factors for the development of hepatic insulin resistance and liver inflammation. 

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How regular exercise can protect against fatty liver associated diseases