Visceral Fat Volume correlates with Hepatic Fibrosis in NAFLD Patients
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-09-08 04:30 GMT | Update On 2022-09-08 10:22 GMT
Study in JAPI aimed to calculate visceral fat volume at the L3-L4 vertebral level and its association with hepatic fibrosis assessed by transient elastography. The spectrum of non alcoholic fatty liver disease includes simple steatosis, nonalcoholic steatohepatitis (NASH), advanced fibrosis, and cirrhosis.All patients above 18 years undergoing computed tomography (CT) during the study period...
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Study in JAPI aimed to calculate visceral fat volume at the L3-L4 vertebral level and its association with hepatic fibrosis assessed by transient elastography. The spectrum of non alcoholic fatty liver disease includes simple steatosis, nonalcoholic steatohepatitis (NASH), advanced fibrosis, and cirrhosis.
All patients above 18 years undergoing computed tomography (CT) during the study period with nonalcoholic fatty liver disease were included. Transient elastography was done. Patients were categorized to advanced fibrosis (>10 kPa) and without advanced fibrosis (<10 kPa). The area under the receiver operating characteristic (AUROC) curve was plotted.
Sixty-four patients comprised 36 males and 28 females. Thirty-one (46%) were having advanced fibrosis (transient elastography>10 kPa) and 34 (54%) patients were without advanced fibrosis. Hence, it was concluded that age, weight, BMI, and visceral fat volume measured at L3–L4 level, HbA1c, FBS, and ferritin were independent predictors of advanced fibrosis.
Ref: Varghese J, Devadas K, Joseph RC, et al. Assessment of Visceral Fat Volume and Its Correlation with the Severity of Hepatic Fibrosis in Patients with NAFLD. J Assoc Physicians India 2022;70(9):23–24.
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