Indian Scientists Create Nanomaterial Enabling Brain Cell Activation Without Surgery

Published On 2025-09-24 12:00 GMT   |   Update On 2025-09-24 12:01 GMT
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Scientists at the Institute of Nano Science and Technology (INST) have discovered that a unique nanomaterial called graphitic carbon nitride (g-C₃N₄) can stimulate brain cells without invasive tools like electrodes or lasers. Published in ACS Applied Materials & Interfaces, the study shows this biocompatible material enhances neuron growth, maturity, and communication by responding to the brain’s electrical signals. It also boosts dopamine production in lab-grown brain-like cells and reduces harmful proteins linked to Parkinson’s disease in animal models.

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Unlike current treatments such as deep brain stimulation, which require surgery, g-C₃N₄ naturally interacts with neurons by generating tiny electric fields that open calcium channels, promoting cell growth and connectivity. Acting like a smart switch, it activates only during the neuron’s resting state to prevent fatigue. This breakthrough offers promise for non-invasive therapies targeting neurodegenerative disorders like Alzheimer’s and Parkinson’s. Researchers believe it could revolutionize neuromodulation and advance futuristic brain-computer technologies. Further human studies are underway to confirm safety and effectiveness.

Reference: Singh, S., Kumar, S., Kumar, G., Mukherjee, S. (2025). Neuro-compatible Biomaterials: Pioneering Solutions for Brain and Nerve Disorders. In: Kumar, G., Mukherjee, S., Kumar, S. (eds) Biomaterials and Neurodegenerative Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-97-9959-6_3

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