10/March/2022 Top Medical Bulletin

Here are top medical stories for the day:

Side effects of multiple sclerosis drugs can be reduced Nature communications 

 Multiple sclerosis prevalence has increased worldwide, also the failure of drugs and its outcomes in treating has caused severe drawbacks in field of medicine. New investigation from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets. this may be a landmark way for better treatments.

The study published in Nature Communications found the detailed precise molecular structure of the multiple sclerosis drug siponimod that interacts with its target, and off-target receptors using a cutting-edge electron microscopy technique.

American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference

According to preliminary research to be presented at the American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference 2022, women who entered menopause very early, before age 40, were found to be more likely to develop dementia of any type later in life compared to women who begin menopause at the average menopause-onset age of 50 to 51 years. Routine exercise, participation in leisure and educational activities, not smoking and not drinking alcohol, maintaining a healthy weight, getting enough vitamin D and, if recommended by their physician, possibly taking calcium supplements, might help women prevent dementia who experience early menopause.