12/March/2022 Top Medical Bulletin

Here are top medical stories for today:    

 Home blood pressure reading more accurate than one taken at clinic

Blood pressure measurements routinely taken at home are more likely to provide the basis for accurate diagnoses of hypertension than those taken in a clinic setting, according to a new study led by Kaiser Permanente investigators.

The findings come from a randomized controlled trial of 510 adults who visited one of 12 Kaiser Permanente primary care centers in Western Washington between 2017 and 2019 published today in the Journal of General Internal Medicine.

For more information check out he full story on the link below:

Home blood pressure reading more accurate than one taken at clinic 

 Exercise to reduce the risk of Alzheimer's disease

Frequent and regular physical exercise is an important component in the prevention of some diseases such as heart disease, cardiovascular disease, Type 2 diabetes and obesity. Physical fitness has been linked to a lower risk of Alzheimer's disease (AD), but even moderate levels of cardiorespiratory fitness offer some protection. The Study will be presented in American Academy of Neurology. The findings suggest that people can work toward making incremental changes and improvements in their physical fitness, which may help decrease their risk of dementia. The fact that you can reduce risk for Alzheimer's disease by simply increasing activity levels is very promising, especially since there are no adequate treatments to prevent or stop the progression of the disease.

Use of cusp-overlapping projection in TAVR reduces rate of permanent pacemaker implantation

 A novel cusp-overlapping projection (COP) technique was shown to significantly reduce the rate of permanent pacemaker implantation (PPMI) in self-expanding (SE) transcatheter heart valve (THV) implantation versus the classical implantation technique, states a recent study. Also, both the techniques were found to have similar rates of complications.

"The findings imply that the COP implantation technique is a safe and feasible modification to the transcatheter aortic valve replacement (TAVR) protocol, " Isaac Pascual, Research Institute of the Principado de Asturias, Oviedo, Spain, and colleagues wrote in their study published in the journal JACC: Cardiovascular Interventions. "This is the first study to systematically evaluate this approach for SE THVs in different populations."

For more information check out he full story on the link below:

Use of cusp-overlapping projection in TAVR reduces rate of permanent pacemaker implantation: JACC

Prediabetic Smokers likely to have High Risk of Albuminuria  

Smoking is attributed to both micro-and macrovascular complications at any stage of metabolic deregulation including prediabetes, particularly those who develop the disease at a young age. A recent study suggests that smokers with prediabetes are at a higher risk of albuminuria than those with diabetes. The study findings were published in the SSRN's Preprints as a preprint with The Lancet on February 08, 2022.

Current global diabetes prevention programmes appear to be glucocentric and do not fully acknowledge the ramifications of cardiorenal risk factors in smokers. A more holistic approach is needed to prevent vascular complications in people with prediabetes and diabetes. T

For more information check out he full story on the link below:

Prediabetic Smokers likely to have High Risk of Albuminuria

GLP-1 Receptor Agonists Have better Outcomes Than DPP4 Inhibitors in Type 2 Diabetes patients & Chronic Kidney Disease

Chronic kidney disease (CKD) and end-stage kidney disease (ESKD) are contributors to the health burden and are associated with increased mortality and cardiovascular events. Type 2 diabetes is the most common cause of CKD, and both diabetes and CKD are associated with increased all-cause mortality and increased rates of infection and cardiovascular events.

A recent study suggests that the use of GLP-1 receptor agonists was associated with better outcomes compared with the use of DPP-4 inhibitors among patients with type 2 diabetes and advanced-stage chronic kidney disease. The study findings were published in the JAMA Network Open on March 07, 2022.

For more information check out he full story on the link below:

GLP-1 Receptor Agonists Have better Outcomes Than DPP4 Inhibitors in T2D patients & CKD