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Here are the top medical news for the day:
Paxlovid, a COVID-19 Drug may interact with common heart medications
A review paper published in the Journal of the American College of Cardiology examines the potential drug-drug interactions (DDIs) between Paxlovid and commonly used cardiovascular medications, as well as potential options to mitigate severe adverse effects.
Paxlovid received emergency use authorization from the U.S. Food and Drug Administration in December 2021 as an oral antiviral agent for the treatment of symptomatic, non-hospitalized adults with mild to moderate COVID-19 infection who are at high risk for progression to severe disease. Patients with heart disease and other risk factors, including diabetes, high blood pressure, chronic kidney disease and smoking make up a large portion of the high-risk population for whom Paxlovid is beneficial.
Reference:
Sarju Ganatra et al,Cardiovascular Drug Interactions With Nirmatrelvir/Ritonavir in Patients With COVID-19: JACC Review Topic of the Week,Journal of the American College of Cardiology,DOI: 10.1016/j.jacc.2022.08.800
Mediterranean diet, as opposed to popular belief, does not decrease dementia risk
A number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that two diets including the Mediterranean diet are not linked to a reduced risk of dementia. The study is published in the online issue of Neurology journal.
The Mediterranean diet includes a high intake of vegetables, legumes, fruits, fish and healthy fats such as olive oil, and a low intake of dairy products, meats and saturated fatty acids.
Reference:
Isabelle Glan,AMERICAN ACADEMY OF NEUROLOGY,Neurology
Hot flashes could also be hard on the heart
It's estimated that upward of 70% of women experience hot flashes sometime during the menopause transition. Although it has long been accepted that hot flashes can affect mental health and quality of life, accumulating research suggests a link between them and cardiovascular disease risk in women.
Cardiovascular disease is the leading cause of death in women, with the risk accelerating in midlife during the menopause transition. Large epidemiologic cohort studies, as well as clinical studies using physiologic assessments of vasomotor symptoms, have produced evidence linking hot flashes and risk of heart disease.
Reference:
Dr. Rebecca Thurston et al, THE NORTH AMERICAN MENOPAUSE SOCIETY (NAMS), MEETING 2022 Annual Meeting of The North American Menopause Society (NAMS)
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