Medical Bulletin 17/September/2022
Here are the top medical news for the day:Diet could play a role in cognitive function across diverse races and ethnicitiesThe team found that certain plasma metabolites—substances created when the body breaks down food—were associated with global cognitive function scores across the diverse set of races and ethnicities. Their results are published in Alzheimer's &...
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Here are the top medical news for the day:
Diet could play a role in cognitive function across diverse races and ethnicities
The team found that certain plasma metabolites—substances created when the body breaks down food—were associated with global cognitive function scores across the diverse set of races and ethnicities. Their results are published in Alzheimer's & Dementia.
Nowadays, researchers can discover biomarkers associated with health changes and diseases by utilizing approaches like metabolomic profiling, which can survey thousands of metabolites within blood samples. An initial study in Boston looking at older adults of Puerto Rican descent found a series of metabolites that were associated with measured cognitive functions.
Reference:
Tamar Sofer,Granot-Hershkovitz et al. "Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition."Alzheimer s & Dementia,DOI: 10.1002/alz.12786
Is it really healthy to restrict protein intake for kidney transplant recipients?
Conventional wisdom holds that low protein intake is essential for kidney disease patients. However, scientists from Osaka Metropolitan University demonstrated that it might not always be the case with their recent study on the relationship between protein intake and skeletal muscle mass in kidney transplant recipients.
Since excessive protein intake worsens kidney function, it is commonly believed that patients with chronic kidney disease, including kidney transplant recipients, should limit protein intake to protect their kidneys. On the other hand, it has been suggested that severe protein restriction may worsen sarcopenia and adversely affect prognosis.
Reference:
Akihiro Kosoku et al,Influence of protein intake on the changes in skeletal muscle mass after kidney transplantation,Clinical Nutrition,DOI: 10.1016/j.clnu.2022.07.028
Excessive smartphone screen time linked to earlier puberty onset
Exposure to blue light, via regular use of tablets and smartphones, may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented at the 60th Annual European Society for Paediatric Endocrinology Meeting.
Melatonin levels are overall higher during pre-puberty than in puberty, which is believed to play a role in delaying the start of puberty. Puberty is a complex process that involves co-ordination of several body systems and hormones.
Reference:
Dr Aylin Kilinç Uğurlu et al,MEETING: European Society for Paediatric Endocrinology Annual Meeting (ESPE 2022)
Infants, young children finally get relief from eczema's terrible itch
The first study to treat moderate-to-severe eczema in infants and children 6 months to 5 years old with a biologic drug rather than immune-suppressing medications shows the drug was highly effective in reducing the signs and symptoms of moderate-to-severe eczema, reported researchers involved in a new multi-site international phase III study led by Northwestern Medicine.
A 16-week course of dupilumab, a medication that targets a key immune pathway in allergies, resulted in more than half the children having at least a 75% reduction in signs of eczema and highly significant reductions in itch with improved sleep.
Reference:
Dr. Amy Paller et al,Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial,The Lancet
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