Medical Bulletin 19/January/2023

Here are the top medical news for the day:

TyG index closely associated with progression of depression

A recent study published in the Journal of Nutrition, Metabolism, and Cardiovascular Diseases found that baseline triglyceride glucose (TyG) index is closely associated with progression of depression. Also, from a metabolic perspective, TyG index monitoring requires more attention for mental health managements.

Cerebral symptoms are common among individuals with non-communicable conditions, while the longitudinal association between triglyceride glucose (TyG) index, indicator of metabolic health, and progression of depression remains unclear. So, this study by Lan Zheng and team aimed to check the association of birth TyG indicator and depression progression in middle-aged and elder grown-ups.

Reference:

Zheng, L., Cui, C., Yue, S., Yan, H., Zhang, T., Ding, M., Sun, Q., He, C., & Ren, H. (2022). Longitudinal association between triglyceride glucose index and depression progression in middle-aged and elder adults: A national retrospective cohort study. Nutrition, Metabolism, and Cardiovascular Diseases: NMCD. https://doi.org/10.1016/j.numecd.2022.11.015

Talking therapies reduce anxiety and depression in working age heart patients

Group therapy relieves psychological distress, improves quality of life and results in fewer readmissions for heart problems, according to a study published in European Heart Journal, a journal of the European Society of Cardiology (ESC).

The study included 147 working age cardiac patients with psychological distress, which was defined as a Hospital Anxiety and Depression Scale (HADS) score of 8 or more for anxiety and/or depression. The average age was 54 years and 67% were men. Participants were randomised to five sessions of group CBT plus usual cardiac rehabilitation (CBT group) or cardiac rehabilitation alone (control group).

Reference:

Talking therapies reduce anxiety and depression in working age heart patients; JOURNAL European Heart Journal, DOI: 10.1093/eurheartj/ehac792

Long-term cryopreservation maintains pluripotency of stem cells of the apical papilla

A recent study has been published in the International Journal Of Dentistry establishing the long-term effect of cryopreservation of the stem cells of apical papilla extracted from the apical papilla of a tooth in its developing stage. These cells are considered as an important part of dental stem cells & are useful in Regenerative Endodontic Procedures (REPs).

Regenerative Endodontic Procedures (REPs) include a triad of three important factors: Stem cells, growth Factors & scaffolds. Apical papilla has been an incredible source for providing stem cells for regenerative endodontic procedures as it is a developing tissue formed and present only at the time of tooth development. Moreover, stem cells can be extracted from the same before the completion of the root formation.

Reference:

https://www.hindawi.com/journals/ijd/2022/6004350; International Journal Of Dentistry