Medical Bulletin 20/November/2021

Published On 2021-11-20 11:10 GMT   |   Update On 2021-11-20 11:10 GMT
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Retinal nerve thickness predicts depression

According to a new study, having a thinner retinal nerve fiber layer (RNFL) is related with a greater frequency of clinically significant depressed symptoms and more depressive symptoms over time. As a result, neurodegeneration may be linked to the early pathobiology of late-life depression.

This study was performed by Frank C. T. van der Heide and team, results of which are published in the Journal of American Medical Association on 16th November, 2021.

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Robotic Knee Replacement tied to lower complication
A study by Dr. Geoffrey Westrich and colleagues at Hospital for Special Surgery (HSS) found knee replacement performed with robotic assistance led to a lower complication rate in the first three months following surgery. The research, which appeared in the October issue of
Arthroplasty Today,
also found that the nationwide use of a robotic system in knee replacement increased more than 2,000% from 2010 to 2018.

"The use of computer-assisted navigation and robotic assistance for total knee replacement has increased tremendously and shows no sign of slowing down," Dr. Westrich said. "Among American Association of Hip and Knee Surgeons attending the 2020 annual meeting, 77% of respondents indicated that they used technology in their surgical cases. The most common reason they cited was to increase surgical precision."

For more details, check out the full story on the link below:

Robotic Knee Replacement Tied To Lower Complication Rate Upto 3 Months After Surgery

Thiazolidinediones reduce risk of NAFLD

Thiazolidinediones (TZDs) are beneficial for certain selected patients at risk of Non-Alcoholic Fatty Liver Disease (NAFLD), according to a study published in the Hepatology.

Thiazolidinediones (TZDs) and glucagon-like peptide-1 (GLP-1) receptor agonists are potential pharmacological treatment options for patients at risk of Non-Alcoholic Fatty Liver Disease (NAFLD). Therefore, a group of researchers examined the association between the risk of NAFLD and the use of TZDs and GLP-1 receptor agonists compared with the use of sulfonylureas (SUs) and insulins. Additionally, the researchers calculated the incidence of HCC in users of TZDs and GLP-1 receptor agonists.

For more details, check out the full story on the link below:

Thiazolidinediones May Significantly Reduce Risk Of NAFLD, Finds Study


Inflammatory diets increase risk of dementia

Diets with higher inflammatory potential were associated with an increased risk of incident dementia, find researchers at Columbia University in New York City and Kapodistrian University of Athens Medical School in Greece. This suggests that people who consume an anti-inflammatory diet that includes more vegetables, fruits, beans, and tea or coffee may be at lower risk of developing dementia later in life.

According to the results from the population-based study, each unit increase in dietary inflammatory index scores was associated with a 21% higher risk of dementia over 3 years. The study appears in Neurology, the medical journal of the American Academy of Neurology.

For more details, check out the full story on the link below:

Inflammatory Diets May Increase Risk Of Incident Dementia, Finds Study

Stillbirth, miscarriage pose risk of CHD in offspring

A new study found that offspring born to mothers who had a previous SA or stillbirth, especially multiple episodes, or who had pre-pregnancy type 2 diabetes were more likely to be diagnosed with congenital heart disease (CHD). The findings of the study were published in The Journal of American Medical Association (JAMA) on 10th November 2021.

CHD is the most common congenital anomaly, with a global prevalence ranging from 9 to 18 per 1000 live births in 2017, resulting in 2.6 million deaths globally. CHD etiology is complex, and epidemiological studies have suggested that a genetic or environmental cause can be identified in 20% to 30% of CHD cases.

For more details, check out the full story on the link below:

Mothers With History Of Stillbirth, Miscarriage Pose Higher Risk Of CHD In Offspring: JAMA

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