Here are the top medical news for the day:
Link between schizophrenia and vascular alterations in the brain uncovered in study
A recent study suggests that schizophrenia may be associated with alterations in the vascularization of certain brain regions. Researchers found a link between astrocytes (central nervous system cells) from patients with schizophrenia and formation of narrow blood vessels.
In the study, the researchers focused on the role of astrocytes in development of the disease. These glial cells are housekeepers of the central nervous system and important to its defense. They are the central elements of the neurovascular units that integrate neural circuitry with local blood flow and provide neurons with metabolic support.
Reference:
Juliana Minardi Nascimento et al, Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization, Molecular Psychiatry
Study finds defects in mitotic and telomere function to increase risk of sarcomas
Heritable pathogenic defects in genes related to mitosis and telomere function may specifically increase the risk for sarcomas - rare cancers that develop in muscles, bones, and other connective tissues, researchers report.
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