Medical Bulletin 25/January/2024

Despite these advancements, doctors still diagnose the disease based on clinical features, such as the presence of tremors and other common motor symptoms.

In a recent article published in Lancet Neurology, Dr. Lang’s team proposed a new, biologically based model for classifying PD, called SynNeurGe.

Reference: A “radically different” way of looking at Parkinson’s Disease; The Lancet Neurology

One-week FDG PET/CT predicts treatment response in advanced melanoma

Cancer immunotherapy has helped transform the standard of care for many malignancies, but not all patients respond to therapy, and the treatment can cause severe adverse events.Typically, immunotherapy patients are imaged around three months after starting treatment to monitor their progress.

The research team led by Michael D. Farwell, an associate professor of radiology at the Hospital of the University of Pennsylvania hypothesized that by using F-fluorodeoxyglucose (FDG) PET/CT, which is one of the most common and readily available ways to test for cancer, patients could experience metabolic changes in tumors after a week on immunotherapy.

The study is published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

Reference: One-week FDG PET/CT predicts treatment response in advanced melanoma; Clinical Cancer Research