COVID-19: A major contributor to Sepsis, new study reveals
Recent research led by investigators at Brigham and Women’s Hospital has unveiled a startling revelation: during the early stages of the COVID-19 pandemic, the SARS-CoV-2 virus, responsible for COVID-19, was a more prevalent and deadly cause of sepsis than previously believed.
Viral sepsis has received limited attention in previous research, primarily due to the scarcity of comprehensive data. To obtain a more precise understanding of sepsis cases, the research team tapped into electronic health records from Mass General Brigham hospitals during the study period.
The team assessed the incidence and mortality rates of SARS-CoV-2-associated sepsis using clinical criteria adapted from the Center for Disease Control and Prevention’s (CDC) sepsis surveillance definition. This criteria incorporated positive SARS-CoV-2 tests and clinical indicators of organ dysfunction. Analyzing EHR data spanning from March 2020 to November 2022, the researchers identified 431,017 hospitalizations involving 261,595 individuals.
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