COVID-19 antibody treatments aren't as effective for new variants

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2022-06-11 04:30 GMT | Update On 2022-06-11 04:30 GMT

The study published in Biochemistry journal is the first to explore the effects of multiple mutations in the evolution of SARS-CoV-2 variants. The findings can help scientists better understand the properties of current and new variants.

Nearly half of 4.3 million variant sequences that contain any of these three mutations have all three occurring together. Although individual mutations have both beneficial and deleterious effects, when they come together, these effects get cancelled out, leading to improved selection of the mutations together.

The researchers found the three mutations performed very distinct and specific roles that contributed toward improving the virus fitness and build the case for their positive selection, even though individual mutations have deleterious effects that make them prone to negative selection. When these mutations come together, the deleterious effects are mitigated due to the presence of compensatory effects.

Hence, the authors concluded that the collective effect of these mutations is far more advantageous for virus fitness than the individual mutations and the presence of multiple mutations improves the selection of individual mutations.

Full View

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Comments Policy

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

COVID-19 antibody treatments aren't as effective for new variants

Similar News

Real-World Case Insight: Triple FDC Therapy in a Young Diabetes Patient - Dr Naresh Kumar

Evidence-Based Recommendation by Indian Pediatric Experts on the Use of Acid-Reducing Medications in Children

Study Reveals Why Some People with Obesity Avoid Disease Through Genetic Mapping

Acupuncture May Ease Chronic Back Pain and Boost Function in Older Adults: Study Shows

India Sees Sharp Rise in Deaths from Lifestyle Diseases: Global Study Finds

WHO Updates Essential Medicines List, Adds Cancer, Diabetes and Obesity Drugs

Common Nasal Spray Cuts COVID Risk by Two-Thirds in Clinical Trial

Glipizide and Metformin FDC - Effective, Safe and Cost-Effective in T2D: Latest Indian Real-World Study