High-doses of Covid medicines not effective in India than Europe

According to a new study published in The Lancet Regional Health - Southeast Asia journal higher doses of the COVID-19 drug, dexamethasone, may have less beneficial effects for patients in India as compared with those in Europe,

The researchers in the study evaluated how strong dose of dexamethasone worked for COVID-19 patients. It considered factors like patient differences and health systems.

Their team, including researchers from Copenhagen University Hospital - Rigshospitalet, Denmark found that bigger dose of dexamethasone (12 mg) did not seem to be as good as the usual dose (6 mg) for COVID-19 patients in India.

''Our analysis suggests higher dose dexamethasone may have less beneficial effects for patients in India as compared with those in Europe; however, the evidence is weak, and this could represent a chance finding,'' the authors of the study noted.

The study emphasises that where patients are from can affect how well treatments work. It pointed out that in lower-middle-income countries like India, there are unique challenges that might make the treatment not work as well.

However, the good news is that the bigger dose didn't cause more problems for Indian patients, which is important for their safety, the researchers said. They said this is just one study, and more research is needed to be sure of the findings.

The study also reminds us that treatments might work differently in different parts of the world, according to the researchers.

Reference: The Lancet Regional Health - Southeast Asia