How recovery progresses following inflammation triggered by injury or illness
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-08-23 03:45 GMT | Update On 2022-08-23 03:45 GMT
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what differentiates a good inflammatory recovery from a bad one? A new study, led by researchers at Harvard Medical School and Massachusetts General Hospital, published in Nature Communications, yields critical clues. The scientists identified universal features of the inflammatory responses of patients who successfully recovered after surgery or acute illnesses such as COVID-19, heart attack, and sepsis. These features, they discovered, include precise paths that white blood cell and platelet counts follow as they return to normal.
Because inflammation occurs in patients who are already sick, it can be a complicated process to study. Thus, the researchers knew that to isolate common features, they would need to study inflammatory recovery in a highly controlled setting. "We needed to find a situation where everybody starts off in the same generally stable state of health, and then they all get a similar inflammatory stimulus at a specific time," explained first author Brody Foy, a research fellow in systems biology at HMS and Mass General.
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