Immune response to COVID-19 strengthens over time: Study

Their findings suggest that vaccine boosters should be spaced no more frequently than a year apart, at least among healthy people. Their findings suggest that the magnitude, potency and breadth of hybrid immune response all increased with a longer time period between exposure to the virus — whether through vaccination or natural infection.

Further, the research team found that it didn’t matter whether someone developed hybrid immunity by getting vaccinated after contracting COVID-19 or after a breakthrough infection following vaccination. Both groups developed an equally potent immune response.The findings suggest long-lasting potency of so-called “memory cells.”

Reference:

Fikadu Tafesse et al,An extended interval between vaccination and infection enhances hybrid immunity against SARS-CoV-2 variants,JCI Insight,doi 10.1172/jci.insight.165265