New nasal vaccine strategy could improve COVID-19 protection

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2022-11-17 03:30 GMT | Update On 2024-02-15 06:25 GMT

Currently many vaccines against SARS-CoV-2 have substantially been found to reduce mortality and severe progression of the disease, but protection against infection is less effective. Vaccinated individuals are still catching COVID-19 and can spread the infection, so breakthrough infections are still occurring.

Researchers from the Centenary Institute and the University of Sydney have developed a new nasal vaccination strategy that induces potent lung immunity and protection against the SARS-CoV-2 coronavirus.

The new vaccine approach has been tested successfully in mice and has the potential to be a powerful tool for enhancing protection against COVID-19 infection and minimising ongoing viral spread. Made up of the SARS-CoV-2 spike protein and an adjuvant called Pam2Cys (a molecule that helps stimulate a stronger immune response in the body.

This vaccine differs from most current COVID-19 vaccines in that it enables generation of an immune response directly in those areas of the body that are likely to be the first point of contact for the virus - the nose, airway and lungs. This may help explain the vaccine's effectiveness.

Reference:

Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice. DOI:https://www.nature.com/articles/s41467-022-34297-3.

Full View

Article Source : Nature Communications

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Comments Policy

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

New nasal vaccine strategy could improve COVID-19 protection

Similar News

India Sees Sharp Rise in Deaths from Lifestyle Diseases: Global Study Finds

WHO Updates Essential Medicines List, Adds Cancer, Diabetes and Obesity Drugs

Common Nasal Spray Cuts COVID Risk by Two-Thirds in Clinical Trial

Glipizide and Metformin FDC - Effective, Safe and Cost-Effective in T2D: Latest Indian Real-World Study

Study Reveals Potassium-Rich Foods May Lower Irregular Heartbeat Risk

Study Reveals Daily Intake of Five Mushrooms May Reduce Alzheimer's and Heart Disease Risk

Managing Nasal Congestion in Allergic Rhinitis: Whats the Mechanism of Action of Allegra D ?

The Prediabetes Show, Episode 4: Metformin in Prediabetes - A Vaccination Pill for Diabetes Prevention in 65 Countries