Researchers Highlight RSV Vaccine Less Effective for Immunocompromised People
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Johns Hpkins Medicine researchers have shown that people 60 years or older with weakened immunity, primarily organ transplant recipients who take immunosuppressive medications do not respond as strongly to vaccines against the respiratory syncytial virus (RSV) as people in the same age group with normal immune function. The study was published in theJournal of the American Medical Association (JAMA).
The researchers used an ongoing, Johns Hopkins Medicine-led national study — the Emerging Pathogens of Concern in Immunocompromised Persons (EPOC) — to follow 38 people (between ages 64 and 72) who self-reported that they are immunocompromised and received either the RSVPreF3-AS01 (also known as Arexvy) or RSVpreF (also known as Abrysvo) vaccine. The study group was evenly split between males and females, with 82% being solid organ transplant recipients and 74% taking two or more immunosuppressive medications.
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