Source specific effects of Interleukin 2 on the immune response
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-06-17 06:00 GMT | Update On 2022-06-25 11:35 GMT
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Researchers have identified source-specific effects of the signalling molecule interleukin 2 (IL2) on the immune response. IL2 is an important signalling molecule that has been harnessed as a biologie therapy for a number of diseases but can result in unwanted side-effects. This study, conducted using new mouse models, found that the immune response to IL2 is dependent on the cellular source of the IL2 production. Their new insight explains the link between IL2 treatments and side-effects, opening up the potential to apply this powerful immune modulator to optimise treatments while avoiding off-target effects.
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