Common kidney Disease needs a kidney biopsy?
Written By : Dr. Nandita Mohan
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-09-21 03:30 GMT | Update On 2022-09-21 03:30 GMT
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Study was performed at a tertiary care teaching hospital in central India to show the current frequency of different types of kidney diseases through histopathological findings. A retrospective analysis of kidney biopsies was done.
Out of the 411 kidney biopsies evaluated, 56.7% were females. The most common indication for kidney biopsy was nephrotic syndrome (NS) (49.9%). However, on analysis of histological patterns, 59.3% of patients had primary glomerular disease (PGD), 28% had secondary glomerular disease (SGD), 5.2% had tubulointerstitial disease (TID), and 6.7% had vascular disease.
In this study, focal segmental glomerulosclerosis (FSGS) was the most common primary glomerular disease followed by membranous nephropathy, minimal change disease, and IgA nephropathy. In patients aged less than 18 years, minimal change disease was the most common primary glomerular disease (26.5%) and focal segmental glomerulosclerosis was the most common primary glomerular disease (30%) in patients aged between 19 and 59 years. In the elderly population (age ≥60 years), membranous nephropathy was the most common (38%) primary glomerular disease.
Researchers concluded that this is the largest study of kidney biopsies patterns from the central part of India, and it presents the combined analysis of the clinical, histopathological, and immunofluorescent features of biopsy-proven kidney diseases in our population.
Reference: Banode RK, Kimmatkar P, Bawankule C, et al. Kidney Disease Patterns diagnosed by Kidney Biopsy: A Single-center Experience from Central India. J Assoc Physicians India 2022;70(9):25–31.
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