Home >  Neurology and Neurosurgery MDTV >  Neurology & Neurosurgery Shorts >  AI Breakthrough helpful...

AI Breakthrough helpful in detecting Hidden Brain Abnormalities in Children with Epilepsy: Study

By - Dr. Bhumika Maikhuri
Published On 2025-02-26 03:00 GMT   |   Update On 2025-02-26 03:00 GMT
Advertisement
Scientists have developed an AI-powered tool that detects 64% of brain abnormalities linked to epilepsy that human radiologists miss. MELD Graph is an AI tool that could drastically change the care for 30,000 patients in the UK and 4 million worldwide with one cause of epilepsy, researchers say.
The study, published in JAMA Neurology by a team at King’s College London and University College London (UCL), shows how the tool significantly improves the detection of focal cortical dysplasia’s (FCDs) which is a leading cause of epilepsy.
Advertisement
In the study, the researchers pooled MRI data from 1185 participants – including 703 people with FCD and 482 controls - from 23 epilepsy centres around the world in the Multicentre Epilepsy Lesion Detection project (MELD). Half of the dataset is from children. They then trained the artificial intelligence tool, MELD Graph, on the scans to detect these subtle brain abnormalities that might otherwise go undetected.
Project lead-author, Dr Konrad Wagstyl, from King’s College London, said: “Radiologists are currently inundated with images they have to review. Using an AI-powered tool like MELD Graph can support them with their decisions, making the NHS more efficient, speeding time to treatment for patients and relieving them of unnecessary and costly tests and procedures.”
Co-author Dr Luca Palma, from Bambino Gesù Children's Hospital, Italy, said: “MELD Graph identified a subtle lesion missed by many radiologists in a 12-year-old boy who had daily seizures and had tried nine anti-seizure medications with no improvement to his condition. This tool could identify patients with surgically operable epilepsy and help with surgical planning – reducing risks, saving money, improving outcomes.”
While the tool is not yet clinically available, the research team have released the AI-tool as an open-source software. They are running workshops to train clinicians and researchers around the world, including Great Ormond Street Hospital and the Cleveland Clinic, in how to use it.
Ref: Ripart M et al., 2025. Detection of epileptogenic focal cortical dysplasia using graph neural networks: a MELD study. JAMA Neurol, Feb 24. doi:10.1001/jamaneurol.2024.5406
Full View
Tags:    
Article Source : JAMA Neurology

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Dr. Bhumika Maikhuri
Comments Policy
Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Similar News

Can Blood Tests Replace Brain Scans for Alzheimer's? New Study Says Yes

Artificial Sweeteners Could Speed Up Brain Aging by 1.6 Years: Study Finds

Head Injuries May Raise Brain Cancer Risk: Major Studies Reveal

Tiny Gold Nanoparticles Show Promise For Early Parkinson's Disease Detection: Study Suggests

New 2025 Hypertension Guidelines Released with Stronger Focus on Brain Health and Early Intervention

Women with Down Syndrome More Vulnerable to Alzheimer's Than Men: Study Finds

Multiple Sclerosis May Begin 15 Years Earlier with Subtle Symptoms: Study Suggests

Can This Common Diabetes Drug Prevent Stroke? Emerging Data Suggests Strong Link