Estrogen might be protective against brain shrinkage

Published On 2022-02-07 12:28 GMT | Update On 2022-02-07 12:28 GMT

Estrogens reportedly is known to affect the development and aging of brain regions that are crucial to higher cognitive functions (like memory) and are implicated in neuropsychiatric disorders such as Alzheimer's disease.

A recent study has revealed an association between more estrogen exposure over the lifetime to greater brain volumes and fewer indicators of brain disease on brain scans in midlife. Reproductive history events signaling more estrogen exposure include longer reproductive span, pre-menopausal status, use of hormonal therapy (HT) and hormonal contraceptives (HC), and a higher number of children.

The study published in Neurology, the medical journal of the American Academy of Neurology on November 3, 2021 found that a number of ways a woman is exposed to estrogen—not having reached menopause, having more total reproductive years, having a higher number of children, using menopause hormone therapy or hormonal contraceptives—were associated with larger gray matter volumes in midlife.

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Is Estrogen Protective Against Risk Of Brain Shrinkage?

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Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

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Estrogen might be protective against brain shrinkage

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