High BMI linked to reduced brain volume and increased white matter lesions, study finds
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A recent study published in Health Data Science, a Science Partner Journal, revealed the significant impact of high cumulative body mass index (BMI) on brain health
The research, led by Associate Professor Han Lv from Beijing Friendship Hospital, Capital Medical University, found that high BMI is associated with smaller brain volume, larger white matter lesions, and abnormal microstructural integrity.
The health burden of overweight and obesity has substantially increased over the last two decades. Characterized by high body mass index (BMI), overweight and obesity are associated with poorer brain health, resulting in accelerated cognitive decline and dementia.
Several cross-sectional studies that acquired BMI and neuroimaging data simultaneously have found that individuals with high BMI had smaller brain volumes and altered white matter (WM) integrity. Several previous studies have analysed the effect of BMI on features of the brain, but the number of neuroimaging features was limited.
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