Lowering Risk of Alzheimer's in Diabetes Patients? Semaglutide May Help, Study Suggests
Advertisement
Researchers at the Case Western Reserve School of Medicine have found that, when compared to seven other anti-diabetic drugs, semaglutide, a popular diabetes and weight-loss drug, may lower the risk of Alzheimer’s disease in people with type 2 diabetes (T2D).
The study, published today in the journal Alzheimer's & Dementia: The Journal of the Alzheimer’s Association, suggests type 2 diabetes patients taking semaglutide had a significantly lower risk of developing Alzheimer’s disease. These results were consistent across different subgroups, including obesity status, gender and age.
The research team—led by biomedical informatics professor Rong Xu—analyzed three years of electronic records of nearly 1 million U.S. patients with type 2 diabetes. The researchers used a statistical approach that mimics a randomized clinical trial.
They found patients prescribed semaglutide had a significantly lower risk for Alzheimer’s disease, compared to those who had taken any of seven other anti-diabetic medications, including other types of GLP-1R-targeting medications.
Reference: Wang W, Wang QQ, Qi X, et al. Associations of semaglutide with first-time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real-world data in the US. Alzheimer's Dement. 2024; 1-12. https://doi.org/10.1002/alz.14313
Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.