New Autism Therapy Shows Promise in Enhancing Cognitive Abilities: study finds
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According to a recent study, cancer drugs could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism. This discovery could lead to therapies for patients with other neurological conditions.
The findings published in Stem Cell Reports highlighted the role of microglia, a type of white blood cell found in the central nervous system, in the formation of the human brain. While research on these cells has advanced significantly in neurodegenerative disorders such as Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis, their role in early neural development has been less understood due to limited access to foetal tissue.
For the study, researchers used brain organoids — “mini brains,” essentially, that mimic the developing brain of an embryo — grown from skin-derived stem cells of consenting patients. Such organoids were created from individuals with Rett syndrome — a disorder primarily found in females that features loss of speech, purposeful use of hands, mobility and muscle tone, among other symptoms as well as from neurotypical individuals.
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