Non–Vitamin K Antagonist Oral Anticoagulants effective in Stroke treatment

Published On 2022-03-03 13:30 GMT   |   Update On 2022-03-03 15:10 GMT
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Stroke management is very crucial as as neurons do not survive longer in case of hypoxia. Current guidelines recommend against use of intravenous alteplase in patients with acute ischemic stroke who are taking non–vitamin K antagonist oral anticoagulants (NOACs).

A recent Results published in JAMA Network concluded that Among patients with acute ischemic stroke treated with intravenous alteplase, use of non–vitamin K antagonist oral anticoagulants within the preceding 7 days was not associated with a significantly increased risk of intracranial hemorrhage.

Study evaluated the safety and functional outcomes of intravenous alteplase among patients who were taking non–vitamin K antagonist oral anticoagulants prior to stroke and compared the outcomes with patients who were not taking long-term anticoagulants. 

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