Using the body’s own cells to treat traumatic brain injury
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More than a million people in the US suffer from a traumatic brain injury (TBI) every year, about 230,000 of them are hospitalized, and almost 70,000 die from TBI-related causes. There is currently no treatment for the damage caused to brain tissue during a TBI, beyond managing a patient’s symptoms. One of the main drivers of TBI-caused damage is a runaway inflammatory cascade in the brain.
Scientists have created a new treatment for traumatic brain injury (TBI) that shrank brain lesions by 56% and significantly reduced local inflammation levels in pigs. The new approach leverages macrophages, a type of white blood cell that can dial inflammation up or down in the body in response to infection and injury.
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