Can Your Genes Reveal If You'll Be Obese as an Adult? Study Provide Insights
A new study published in Nature Medicine has revealed that genetic analysis using data from more than five million individuals can offer powerful insights into who is at risk of developing obesity even from early childhood. Led by researchers from the Universities of Copenhagen and Bristol, the study introduces a new polygenic risk score (PGS) that could help identify children most likely to benefit from early preventive strategies.
Obesity is a growing global concern, with the World Obesity Federation predicting that over half the world’s population could be overweight or obese by 2035. Despite available treatments such as lifestyle changes, surgery, and medications, their accessibility and effectiveness remain limited. This has intensified the search for early detection and prevention approaches.
To develop the polygenic risk score, the research team analyzed the genomes of over five million people, combining data from sources including the Genetic Investigation of ANthropometric Traits (GIANT) consortium and DNA-testing company 23andMe. The polygenic risk score aggregates the small effects of thousands of genetic variantsmany of which influence appetite via the brain into a single predictive score.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.