Combined birth control pill may increase blood clots risk in obese women
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-09-19 03:45 GMT | Update On 2022-09-19 10:07 GMT
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Obese women who use oral contraceptives containing oestrogen and progestin have a 24-fold increased risk of venous thromboembolism (VTE) compared with non-obese women not using the drugs, according to a review paper published today in ESC Heart Failure, a journal of the European Society of Cardiology (ESC).
This review article highlights the latest evidence on the independent effects of obesity and contraceptives, and their synergistic effects, on VTE risk and provides clinical recommendations. VTE refers to a blood clot in a vein and includes two life-threatening conditions: deep venous thrombosis and pulmonary embolism.
The World Health Organization estimates that the global prevalence of obesity nearly tripled between 1975 and 2016 – with 15% of adult women being obese. The risk of VTE increases progressively with body mass index (BMI), and in obese women it is more than double that of non-obese women. Obesity has the most substantial impact on VTE women under 40 years of age, who have a five-fold increased risk compared with non-obese women.
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