Journal Club - Hypertension Control During Pregnancy Crucial, Validates a Large Trial

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2022-04-25 04:00 GMT | Update On 2022-04-25 10:18 GMT

High blood pressure, is very common and it is even more common in pregnancy. high blood pressure happens in 1 in every 12 to 17 pregnancies among women ages 20 to 44. However, with good blood pressure control, you and your baby are more likely to stay healthy.

according to a large, open-label, randomized trial, pregnant women with even mild hypertension should receive blood pressure–lowering medications to reduce the likelihood of adverse outcomes for the mother and the child, Treating to the blood pressure goal in this study reduced the risk of adverse events associated with pregnancy but did not impair fetal growth, reported at the annual scientific sessions of the American College of Cardiology.

In this trial, 2,408 pregnant women with chronic mild hypertension defined as a blood pressure of 160/90 mm Hg were randomized to treatment with a goal blood pressure of less than 140/90 mm Hg or no treatment unless the blood pressure rose to at least 160/105.

All women had singleton pregnancies. Severe hypertension (at least 160/105 mm Hg) was an exclusion criterion, as were several comorbidities, such as kidney disease. For the composite primary outcome of severe preeclampsia, medically indicated preterm birth at less than 35 weeks of gestation, placental abruption, or fetal/neonatal death, the treatment of hypertension versus no treatment showed a relative risk reduction of 18%.

An increase in preeclampsia risk in women whose fetus was small for gestational age (SGA), a theoretical consequence of reductions in arterial pressure, was not seen. Researchers concluded that there has to be protocols for treating mild hypertension in pregnancy and that the American College of Obstetricians and Gynecologists (ACOG) is evaluating these data for changing their current guidelines for managing hypertension during pregnancy.

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Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

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Journal Club - Hypertension Control During Pregnancy Crucial, Validates a Large Trial

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