Maternal Exposure to Metformin Safe: Proves a Largest Cohort study

A recent study published in BMJ Open Diabetes Research and Care, aimed to investigate if maternal pregnancy exposure to metformin is associated with increased risk of long-term and short-term adverse outcomes in the child.

Study was conducted in Finland included singleton children born 2004–2016 with maternal pregnancy exposure to metformin or insulin,3967 participants were given metformin only , 5273 insulin only and 889 combination treatment.

The primary outcomes were long-term offspring obesity, hypoglycemia, hyperglycemia, diabetes, hypertension, polycystic ovary syndrome, and challenges in motor social development.