Maternal Exposure to Metformin Safe: Proves a Largest Cohort study
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A recent study published in BMJ Open Diabetes Research and Care, aimed to investigate if maternal pregnancy exposure to metformin is associated with increased risk of long-term and short-term adverse outcomes in the child.
Study was conducted in Finland included singleton children born 2004–2016 with maternal pregnancy exposure to metformin or insulin,3967 participants were given metformin only , 5273 insulin only and 889 combination treatment.
The primary outcomes were long-term offspring obesity, hypoglycemia, hyperglycemia, diabetes, hypertension, polycystic ovary syndrome, and challenges in motor social development.
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