Maternal fat metabolism and fetal abdominal growth may affect child weight and adiposity
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-08-29 04:30 GMT | Update On 2022-08-29 04:30 GMT
Advertisement
A new study, led by researchers at the University of Oxford in collaboration with the University of California in Lancet Diabetes & Endocrinology identifies, as early as the 5th month of pregnancy, patterns of fetal abdominal growth associated with maternal lipid metabolites that track newborn growth, adiposity and development into childhood. These fetal growth patterns are also associated with blood flow and nutrient transfer by the placenta, demonstrating a complex interaction between maternal and fetal nutrition early in pregnancy that influences postnatal weight and eventually adult health.
The researchers monitored the growth inside the womb of over 3,500 babies in six countries using serial fetal ultrasound scans throughout pregnancy, and analysed blood samples taken from the women early in pregnancy and from the umbilical cord at birth. They then monitored the growth and development of the infants until 2 years of age.
Stephen Kennedy who co-led the study, said: 'This landmark study has provided valuable new insights into the biological origins of childhood obesity, which is one of the most pressing public health issues facing governments around the world. The findings could contribute to earlier identification of infants at risk of obesity.'
Ref:
José Villar et al,''Fetal abdominal growth trajectories, associated with maternal metabolite signatures early in pregnancy, are footprints for childhood growth and adiposity' , Lancet Diabetes & Endocrinology https://doi.org/10.1016/S2213-8587(22)00215-7
Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.