Maternal tenofovir with Vaccination to prevent Vertical Hepatitis B transmission

This study was carried out by Ha T. Nguyen and colleagues to examine the efficiency and safety of pharmaceutical therapies to prevent vertical transmission of the hepatitis B virus.

Cochrane, Medline, and Scopus databases were searched for this study up to October 28th, 2020. All randomized controlled studies that reported vertical hepatitis B viral transmission with the pharmaceutical intervention were properly searched and included in the analysis. The Cochrane Risk-of-Bias tool Version 2 was used to assess the risk of bias. The effectiveness of the treatment was calculated using a stratified network meta-analysis which was based on maternal hepatitis B envelope antigen status.